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Ethinylestradiol
Clinical data
Pronunciation/ ˌ ɛ θ ɪ n ɪ l ˌ iː s t r ə ˈ d aɪ . əl /
Trade namesNumerous
AHFS/Drugs.comInternational Drug Names
MedlinePlusa604032
License dataEU  EMA:  by INN
Pregnancy categoryX (USA)
Routes of administration• By mouth (tablet) • Transdermal (patch) • Vaginal (ring)
Drug classEstrogen
ATC codeG03CA01 ( WHO ) L02AA03 ( WHO )
Legal status
Legal statusIn general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability38–48% [3] [4] [5]
Protein binding97–98% (to albumin; [6] is not bound to SHBG) [7]
MetabolismLiver (primarily CYP3A4) [2]
Metabolites• Ethinylestradiol sulfate [8] [9] • Others [8] [9]
Elimination half-life7–36 hours [10] [3] [2] [11]
ExcretionFeces: 62% [10] Urine: 38% [10]

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